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Analysis of atherosclerosis in the aortic sinus revealed that DT-109 treatment led to a significant reduction in the plaque area (by 32.4%, p˂0.01, Fig

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The sustained tonic GH/IGF-1 elevation it produces — rather than pulsatile bursts — is both a research advantage (easier to measure steady-state changes in body composition) and a design consideration (it does not replicate physiological GH pulsatility, which may matter in neuroendocrine studies)